Stem Cells and Cardiac Regeneration (Stem Cell Biology and Regenerative Medicine)

This book provides an update of recent advances in the basic and clinical applications of cell-based therapies for myocardial repair and regeneration in ischemic heart disease (IHD) and heart failure (HF). The first sections of the book illuminate basic aspects of stem cells such as definitions, isolation criteria and characterization of embryonic and adult stem cells, as well as pluripotent stem cells and tissue specific progenitor and stem cells. In the following section, the text examines the role of critical regulators of stem cell differentiation in myocardial regeneration, that include circadian rhythyms, microRNAs, epigenetics, microvescicles, and exosomes. The text concludes with a review of the use of stem/progenitor cells in cardiac regeneration and discuss current controversies, unresolved issues, challenges, and future directions. Stem Cells and Cardiac Regeneration is addressed to a wide audience consisting of cardiologists, clinicians, and research scientists, who will learn new concepts in cardiovascular regeneration and repair with special focus on molecular mechanisms and therapeutic potential for cardiovascular regeneration. 

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Stem Cell and Regenerative Medicine

The potential use of stem cells in transplantation for the purpose of tissue regeneration is an exciting area of research currently undergoing rapid development. Implantation of human embryonic or autologous, ex vivo-expanded adult stem cells, particularly in older individuals, could circumvent the limited availability of organs/tissues as well as prevent complications related to immune rejection and disease transmission. Musculoskeletal tissue degeneration is closely associated with aging. Strategies employing autologous adult MSCs from older individuals for transplantation in order to regenerate their own ailing organ or tissues require that we vigorously define MSCs capacity to maintain growth potential and differentiation potential into the desirable cell lineages. We are currently restricted by the limited knowledge about physical parameters, such as biomechanical forces, that influence MSC growth and differentiation capacities. This is particularly important for MSCs isolated from older individuals, for whom little information is available. This special volume aims to serve as an impetus in generating more interest among stem cell researchers and biotechnologists to improve and develop the cell-based therapies of damaged tissue using stem cells.

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FACTORFIVE Regenerative Serum with Human Derived Apidose Stem Cell Growth Factors, Travel Size, 0.34fl oz/10ml

WHAT IS FACTORFIVE? FACTORFIVE is a new type of scientific skincare – one that was created with as much integrity as it was innovation. Our scientifically efficacious, result driven products embody the next generation of regenerative skincare. Using a propriety technique, the Stanford trained scientists behind FACTORFIVE have developed a unique method that harnesses the powerful, anti-aging properties of adipose derived stem cell factors. WHAT ARE THE BENEFITS OF USING FACTORFIVE? Promote human dermal fibroblast proliferation, a primary cell type that makes up the skin. Increase proliferation and migration of human keratinocytes, a primary cell type found in skin, as well as stimulate production of collagen and a variety of growth factors and cytokines involved in cell migration, increased blood flow, vascularization, and cell renewal. Increase collagen and hyaluronic acid synthesis in human dermal fibroblasts, proteins associated with healthy, youthful skin, skin remodeling, and healing. Reverse the damaging effects of UV radiation, fight wrinkle formation, increase cell proliferation, increase collagen production, and decrease expression of MMP1, a gene linked to scar formation. Inhibit proliferation of melanoma cells (skin cancer), protect skin cells from chemical induced oxidative stress, and boost collagen synthesis and cell motility, showing that these factors may help fight skin cancer and the effects of photoaging. Reduce healing time after laser resurfacing and catalyze production of collagen and elastin.

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