The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson’s, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and ‘bench to bedside’. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing clinicians and advanced graduate students.
A look at the future of medicine based on cutting-edge stem cell research
• Shares Dr. Biava’s groundbreaking research on stem cell differentiation stage factors (SCDSFs) as a cellular “reprogramming” treatment for cancer and other degenerative diseases such as psoriasis and Parkinson’s
• Explains how SCDSFs restore communication between cells and the epigenetic code, the information that programs the normal function and growth of every living cell
• Explores how the universe operates like a cosmic information-network and how this new scientific worldview will shape the future of healing and medicine
The universe is not a mechanical system of matter–it operates like a cosmic network that runs on and is connected by information. Information “in-forms” and underlies all of the physical world, including the human body. In this book, Pier Mario Biava, M.D., and Ervin Laszlo, Ph.D., show how this “information” worldview can be applied to healing and medicine and, specifically, how it underlies a revolutionary new approach to cancer and disease treatment, one that works directly with the epigenetic code–the information that programs the function and growth of every living cell.
The authors explain how tumor growth and cellular dysfunction are manifestations of disconnections in the information network of an organism. Unveiling Dr. Biava’s groundbreaking research on stem cell differentiation stage factors (SCDSFs), they explain how SCDSFs work directly with the epigenetic code to reconnect aberrant cells to the body’s information network and reset them to their original function–in the case of cancer cells transforming them from malignant to benign, from dysfunction back to normalcy and health. Dr. Biava’s research on SCDSFs–derived from Zebrafish embryos, which have 95 percent the same proteins as humans–has shown great success in reprogramming and inhibiting cancer cells in clinical trials with patients with advanced liver cancer, as well as success in in vitro studies with 7 different human tumor lines. SCDSFs have also shown promise in the treatment of chronic diseases such as psoriasis and neurodegenerative conditions, including Parkinson’s and Alzheimer’s.
Unveiling the holistic future of medicine, the authors show how we will no longer need to approach the treatment of cancer and other degenerative diseases as a “fight,” but as a restoration of our cells’ original programming. With the advent of Information Medicine, we now have the power to program ourselves to heal.