Regenerative Medicine and Stem Cell Therapy for the Eye (Fundamental Biomedical Technologies)

This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation  and cell replacement therapy; gene therapy; and in vitro disease modelling.  Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering.   
This book also
  • Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular disease
  • Provides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domain
  • Offers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineers
  • Examines the connection between cell therapy and gene editing, in particular relation to ocular disease

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Stem Cells and Cardiac Regeneration (Stem Cell Biology and Regenerative Medicine)

This book provides an update of recent advances in the basic and clinical applications of cell-based therapies for myocardial repair and regeneration in ischemic heart disease (IHD) and heart failure (HF). The first sections of the book illuminate basic aspects of stem cells such as definitions, isolation criteria and characterization of embryonic and adult stem cells, as well as pluripotent stem cells and tissue specific progenitor and stem cells. In the following section, the text examines the role of critical regulators of stem cell differentiation in myocardial regeneration, that include circadian rhythyms, microRNAs, epigenetics, microvescicles, and exosomes. The text concludes with a review of the use of stem/progenitor cells in cardiac regeneration and discuss current controversies, unresolved issues, challenges, and future directions. Stem Cells and Cardiac Regeneration is addressed to a wide audience consisting of cardiologists, clinicians, and research scientists, who will learn new concepts in cardiovascular regeneration and repair with special focus on molecular mechanisms and therapeutic potential for cardiovascular regeneration. 

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Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy, An Issue of Infectious Disease Clinics of North America (The Clinics: Internal Medicine)

In collaboration with Consulting Editor, Dr. Helen Boucher, Dr. Jo-Ann Young has put together a state-of the-art issue of the Infectious Disease Clinics of North America devoted to Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy. Clinical review articles from expert authors are specifically devoted to the following topics, addressing both the stem cell transplant recipient and the hematologic malignancy patient: Chemotherapy Regimens for Hematologic Malignancies and Issues That Affect Infection; Stem Cell Transplantation Technical Issues That Affect Infection in The Recipient; Complications of Stem Cell Transplantation That Cause Infections; Antimicrobial Prophylaxis and Preemptive Agents and Regimens for the Prevention of Infection; Workup for Fever During Neutropenia; Herpesvirus Infections; Cytomegalovirus Infections; Respiratory Virus Infections; Other DNA Virus Infections; Bacterial Infections; Fungal Infections; Parasitic Infections; Vaccination; and Immunoglobulin Replacement. Readers will come away with the latest information they need to manage infections and improve outcomes in these patients.

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