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Traditional peoples, Native Americans and early ancestral healers knew that eating the organs from a healthy animal would strengthen and support the health of the corresponding organ of the individual. The traditional way of treating a person with a weak heart was to feed the person the heart of a healthy animal. Similarly, eating the kidneys of a healthy animal was believed to support urinary ailments and overall kidney health… Pancreas was fed to people with pancreatic and digestive problems… trachea and other cartilaginous parts (not just the hides!) provided concentrated amounts of connective tissue, cartilage, collagen and other proteins that are now missing from the modern diet.
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Proteins Exclusively Found And Expressed In Bovine Tracheal Cartilage
Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts.
Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside
Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios
Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications