EU Pharmaceutical Legislation Handbook. Vol. 5 Stem Cell Reserch Legislation and Regulations (World Strategic and Business Information Library)

EU Pharmaceutical Legislation Handbook. Vol. 5 Stem Cell Reserch Legislation and Regulations

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Human Embryonic Stem Cells: The Practical Handbook

With this valuable practical guide, three members of the HarvardStem Cell Institute have compiled and edited the definite handbookfor the exciting new field of human embryonic stem cell research.The editors have gathered protocols from scientists with extensivereputation and expertise, describing and comparing currently usedtechniques for the culture of human stem cells and discussing thestrengths and weaknesses of the different approaches.

Human Embryonic Stem Cells: The PracticalHandbook contains the first centralised collection ofmethods used in human embryonic stem cell biology. The book coversthe derivation of human stem cell lines, the obtaining of cellsfrom human stem cell banks, the culturing and characterisation ofthe cells, and the differentiation of the cells in vitro andin vivo. Lastly, almost all of these protocols can also beused for analyzing and manipulating induced pluripotency iPS stemcells. This allows an even greater number of opportunities forthose interested in purusing work in pluripotent stem cells,disease modelling, and other aspects of basic regenerative medicineresearch.

The novel and useful focus of this book sets it apart from otheravailable books:

  • Compares and evaluates the protocols used in leadinglaboratories working on human embryonic stem cells
  • Centred solely on practical protocols for human (not mouse)embryonic stem cell research
  • Includes extensive troubleshooting sections
  • Addresses the different proclivities and behaviours ofindividual human embryonic cell lines
  • Contains techniques currently known only to a small number ofspecialised laboratories worldwide

This handbook represents an essential source of up-to-datepractical information for all cell and developmental biologistsworking with human embryonic stem cells or wishing to enter thefield. It is also essential reading for clinical researchersin areas such as diabetes, cardiovascular disease, and neurologicaldiseases.

Praise from the reviews:

“…a highly readable and useful book… A notablefeature of the book is its air of openness and honesty… Thisbook… will help many to navigate the uncharted waters ofhuman embryonic stem cell biology.” BRITISH SOCIETY FOR CELLBIOLOGY

“… the imaginative solutions in this book can inspire us toget past our most frustrating limitations.” CELL STEM CELL

“… the richness in the details of each protocol presentedwill certainly encourage more scientists to begin studies of Humanpluripotent stem cells…”  REGENERATIVE MEDICINE

“In this fast-moving field, this [handbook] will help driveadvances of more and more researchers.” DIFFERENTIATION

“…a valuable resource for seasoned and noviceresearchers… an excellent addition to the reference collection ofany medical library or research laboratory.” THE AMERICANMEDICAL ASSOCIATION

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Handbook of Theories of Aging, Third Edition

This state-of-the-art handbook will keep researchers and practitioners in gerontology abreast of the newest theories and models of aging. With virtually all new contributors and content, this edition contains 35 chapters by the most highly respected luminaries in the field. It addresses theories and concepts built on cumulative knowledge in four disciplinary areasóbiology, psychology, social sciences, and policy and practiceóas well as landmark advances in trans-disciplinary science. With its explicit focus on theory, the handbook is unique in providing essential knowledge about primary explanations for aging, spanning from cells to societies.

The chapters in the third edition place a strong emphasis on the future of theory development, assessing the current state of theories and providing a roadmap for how theory can shape research, and vice versa, in years to come. Many chapters also address connections between theories and policy or practice. Each set of authors has been asked to consider how theories in their area address matters of diversity and inequalities in aging, and how theories might be revised or tested with these matters in mind. The third edition also contains a new section, “Standing on the Shoulders of Giants,” which includes personal essays by senior gerontologists who share their perspectives on the history of ideas in their fields, and on their experiences with the process and prospects of developing good theory.

Hallmarks of the Third Edition:

  • Highlights important gains in trans-disciplinary theories of aging

  • Emphasizes the future of theory development

  • Provides insights on theory development from living legends in gerontology

  • Examines what human diversity and inequality mean for aging theories

  • Emphasizes interconnections between theory, research, intervention, and policy

  • Underscores international issues with greater representation of international authors

  • Includes section introductions by the editors and associate editors that summarize theoretical developments

Key Features:

  • Highlights variability and diversity in aging processes, from the cellular level of biological aging to the societal level of public policy

  • Provides insights on theory development from living legends in gerontology

  • Offers intergenerational, interdisciplinary, and international perspectives

  • Disseminates a forward-thinking, future-oriented focus in theory development

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