This book discusses the aspects of haploidentical transplants and will shed light on the debates and questions on this burgeoning field and timely topic. Donor selection, graft failure, minimal CD34+ cell requirement, and conditioning regimens used for haploidentical transplants will be written by expert authors dealing with this type of transplants. Approximately one third of the books’ chapters cover logic and basic aspects; the remaining two thirds of the book discuss clinical aspects, outcomes, and future perspectives, thus providing a comphrensive discussion of the topic. Haploidentical transplantation is extremely timely, rapidly-changing area and increasing its use will decrease the need for time-consuming, expensive, unrelated donor search. Moreover, Haploidentical Stem Cell Transplantation brings a set of clear answers to questions of feasibility, advantages over unrelated transplants, cost effectivity and outcome..
Ethics of Emerging Technologies provides the background, insight, and tools for approaching and solving ethical dilemmas across a broad range of topics. The text discusses ethical problems, using examples and reasoning tools that will aid engineers, scientists, managers, administrators, and the public who wish to understand risks, benefits, and possible approaches to resolving conflicts associated with new technologies in the context of the global community.
Solutions we choose to ethical dilemmas accompanying new technologies will profoundly affect future generations. Scientific facts and guides to decision-making for all associated with emerging technologies are presented. Some of the topics are:
* Human health and environmental effects of alternative energy production methods
* Communications and privacy
* Plagiarism and authorship
* Genetic modification of organisms
* Human and animal experimentation
* Synthetic biology and bioterrorism
* Confidentiality in science, engineering, and business communications
* Risks and consequences of enhancing human beings through new technologies
* Cloning of human beings and stem cell research
* Brain modifications
* Space exploration
The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis. This has represented the potential of cancer stem cells in the development of novel and innovative tools for the treatment of metastatic tumors. This book aims to offer a broad framework for obtaining insight into the state-of-the-art knowledge on cancer stem cell biology and highlight the therapeutic implications of these cells in the future of clinical oncology.