Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts.
- Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside
- Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios
- Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications
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This Snap Circuits Extreme Electronics kit lets you create your own experiments and build over 750 exciting projects. Contains more than 80 pieces. Parts are color-coded and projects go together with ease. The Snap Circuits Extreme Electronics Kit makes learning about electronics fun.
- Build over 750 experiments with 80 parts
- Experiments included: sound activated switch, lie detector, adjustable light controller, am radio, rechargeable battery and many more. Use your Windows PC and the included CI-73 Computer Interface manual converts your computer monitor into an oscilloscope and lets you see signals in process in the circuits you assemble
- Parts included: photoresist or, power amplifier, variable capacitor, analog meter, solar cell, computer interface, full color manuals
- Snap-Circuits have received the following Awards: National Parenting Center-Seal of Approval, Creative Child ?Toy of the Year
- Toy Industry Association – Specialty Toy of the Year, Dr. Toy 100 Best Children’s Products, Dr. Toy 10 Best Educational Products
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A look at the future of medicine based on cutting-edge stem cell research
• Shares Dr. Biava’s groundbreaking research on stem cell differentiation stage factors (SCDSFs) as a cellular “reprogramming” treatment for cancer and other degenerative diseases such as psoriasis and Parkinson’s
• Explains how SCDSFs restore communication between cells and the epigenetic code, the information that programs the normal function and growth of every living cell
• Explores how the universe operates like a cosmic information-network and how this new scientific worldview will shape the future of healing and medicine
The universe is not a mechanical system of matter–it operates like a cosmic network that runs on and is connected by information. Information “in-forms” and underlies all of the physical world, including the human body. In this book, Pier Mario Biava, M.D., and Ervin Laszlo, Ph.D., show how this “information” worldview can be applied to healing and medicine and, specifically, how it underlies a revolutionary new approach to cancer and disease treatment, one that works directly with the epigenetic code–the information that programs the function and growth of every living cell.
The authors explain how tumor growth and cellular dysfunction are manifestations of disconnections in the information network of an organism. Unveiling Dr. Biava’s groundbreaking research on stem cell differentiation stage factors (SCDSFs), they explain how SCDSFs work directly with the epigenetic code to reconnect aberrant cells to the body’s information network and reset them to their original function–in the case of cancer cells transforming them from malignant to benign, from dysfunction back to normalcy and health. Dr. Biava’s research on SCDSFs–derived from Zebrafish embryos, which have 95 percent the same proteins as humans–has shown great success in reprogramming and inhibiting cancer cells in clinical trials with patients with advanced liver cancer, as well as success in in vitro studies with 7 different human tumor lines. SCDSFs have also shown promise in the treatment of chronic diseases such as psoriasis and neurodegenerative conditions, including Parkinson’s and Alzheimer’s.
Unveiling the holistic future of medicine, the authors show how we will no longer need to approach the treatment of cancer and other degenerative diseases as a “fight,” but as a restoration of our cells’ original programming. With the advent of Information Medicine, we now have the power to program ourselves to heal.
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