In the face of extraordinary advances in the prevention, diagnosis, and treatment of human diseases, the inability of most tissues and organs, to repair and regenerate after damage is a problem that needs to be solved. Stem cell research is being pursued in the hope of achieving major medical breakthroughs.In maxillofacial region the Regeneration & Repair of damaged periodontal tissue, bone, pulp, and dentin are problems that the dentist faces today. Stem cells have potential to regenerate dentin, periodontal ligament, cementum and can be used for bone defect therapy. The proper utilization of stem cells can full fill the quest to live a long and healthy life which is as old as the appearance of the first cell on earth. So this book basically aims at reviewing the stem cells types, sources, clinical implications both in medical and dental field and along with their roll in tissue engineering.
This authoritative reference presents the modern concepts of mesenchymal stem cells (MSCs) and biomaterials as they pertain to the dental field. The book is organized around three main topics: MSCs biology, advanced biomaterials, and clinical applications. The chapters present basic information on stem cell biology and physiology, modern biomaterials that improve bone tissue regeneration, the biomatrices like platelet-rich fibrin (PRF) used to functionalize the biomaterials surface, the strategic and safe intraoral seats of harvesting, the new sources for MSCs, as well as the future perspectives and new challenges in these exciting fields. The contributors are top scientists with a great deal of experience in regenerative dentistry and biomedical research. They offer an international perspective and are richly cross-disciplinary, representing academia, research, and industry. MSCs and Innovative Biomaterials in Dentistry is indispensable reading for students, researchers, and clinicians who need to stay up-to-date on the cutting-edge developments of tissue engineering and regenerative medicine applied to dental sciences.
Stem cell Research in dentistry is still a relatively unexplored area. In future, stem cells are anticipated to change the face of not only dentistry but the entire medical profession. The endeavor is clearly multidisciplinary in nature, and the practicing dental surgeon has a critical role in it. Playing this role in the most effective way requires awareness of the huge potential associated with the use of stem cells in a clinical setting, as well as proper understanding of the related problems.This book gives a brief insight into the current concept of stem cell research.