This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of different stem cell examples – embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.
Research on the early human embryo has long been recognized as essential to progress in a host of biomedical areas from reproductive medicine to the treatment of pediatric cancers. Now, with the possibility of stem cell research and cell replacement therapies, embryo research holds out the promise of cures for many serious disease conditions such as diabetes and Alzheimer’s disease. Despite its importance, however, human embryo research has met powerful opposition. Drawing on his experience as a member of the NIH’s Human Embryo Research Panel, Green offers a first-hand account of the embryo research debates. In telling this story, he periodically pauses to reflect on some of the leading philosophical challenges posed by embryo research and new interventions at the start of life. Among the questions he examines are: What is the impact of new biological information on our thinking about life’s beginning? May parents risk injuring a child in order to have it? What role should religion play in shaping biomedical policy in a controversial area like this? This is a fascinating insider’s account of one of the most important, if unsuccessful, recent efforts to come to terms with a controversial area of scientific research.
The American Educational JPT-T11 cells of plants poster is used for botanical study, and depicts magnified images of the following cells for detailed examination: onion skin, green cells of a leaf, woody stem (lengthwise and cross section), anther, lily ovary, spirogyra, and bacteria. The poster provides views of cells when used for food and water within the plant as well as cells that provide stem structure for additional information. The JPT-T11 is laminated for durability, and measures 25.5 x 36.0 inches (L x H). (L is length, the horizontal distance from left to right; H is height, the vertical distance from the lowest to highest point.) The poster is suitable for grade 8 and higher and age 13 and older.
Science education products incorporate applied math and science principles into classroom and homeschool-based projects. Teachers in pre-K, elementary, and secondary classrooms use science education kits and products alongside science, technology, engineering, and math (STEM) curriculum to demonstrate STEM concepts and real-world applications through hands-on activities. Science education projects include a broad range of activities, such as practical experiments in engineering, aeronautics, robotics, energy, chemistry, physics, biology, and geology.
American Educational Products, LLC, manufactures and supplies classroom materials and teaching tools for science and math education, as well as early childhood and active play products. The company, founded in 1986, is based in Fort Collins, CO.
- Cells of plants poster for botanical study
- Depicts eight magnified images of plant cells for detailed examination
- Provides view of cells when used for food and water within plant as well as cells that provide stem structure for additional information
- Laminated for durability
- Measures 25.5 x 36.0 inches (L x H)