Stem Cell Therapy and Uses in Medical Treatment (Stem Cells- Laboratory and Clinical Research)

This book presents and discusses current research in the study of stem cell therapy. Topics discussed include stem cell-based therapies; current therapies for multiple sclerosis; stem cell transplantation modulates mRNA gene expression profile in doxorubicin-induced cardiomyopathy; human somatic cell nuclear transfer and parthenogenesis; human cord blood stem cell applications in cell therapy; and, cancer stem cells and neurotrophin in obstetrics and gynaecology.

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Stem Cell Genetics for Biomedical Research: Past, Present, and Future

This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. 

In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.

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Tissue Engineering and the Musculoskeletal System: A Limitless Cure? (Stem Cells-laboratory and Clinical Research: Stem Cells and Regenerative Medicine)

Tissue engineering and regenerative medicine uses a combination of cells, scaffolding and bioreactive factors to treat a variety of pathological conditions and has become a treatment option for many adult diseases. In this book, the authors present current research from across the globe, in the study of the fundamentals, techniques and applications of tissue engineering.

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